Yes, lactose intolerance (or lactase persistence) is a well established genetic trait.
Lactose intolerance in adulthood, however, is caused by another gene called, MCM6, which controls the LCT gene. The "controller" gene normally switches off the LCT gene in adulthood, but in some individuals, does not switch it off due to a mutation, leading to sustained lactase production in the small intestine and the ability to digest lactose in milk throughout life.
There are two types of lactase deficiencies. One, in infancy, where a gene named LCT, responsible for producing the lactase enzyme is mutated and hence produces malfunctioning enzyme, causing affected infants to have a severely impaired ability to digest lactose in breast milk or formula.
Lactose intolerance in adulthood, however, is caused by another gene called, MCM6, which controls the LCT gene. The "controller" gene normally switches off the LCT gene in adulthood, but in some individuals, does not switch it off due to a mutation, leading to sustained lactase production in the small intestine and the ability to digest lactose in milk throughout life.
Worldwide, how many people can digest lactose in milk throughout their lives?
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